WebAug 1, 2024 · The LSKL peptide is a competitive antagonist that inhibits TSP-1-TGF-β activation by preventing the interaction of TSP-1's KRFK sequence with the LAP of latent TGF-β (Fig. 1) [23].This antagonist tetrapeptide has been widely used by our lab and others, along with thbs1 (TSP-1) null animals, to establish TSP-1 as a primary regulator of TGF-β … WebNOL7-transfected cells had decreased angiogenesis, as detected by endothelial cell marker CD31 (PECAM1; 173445), decreased ability to stimulate endothelial cell migration, decreased VEGF (192240) expression, and increased TSP1 (THBS1; 188060) expression. Hasina et al. (2006) concluded that the NOL7 gene plays a role in antiangiogenic activity.
7057 - Gene ResultTHBS1 thrombospondin 1 [ (human)]
WebHuman THBS1/TSP1/Thrombospondin-1 ELISA Kit PicoKine™ (96 Tests). Quantitate Human THBS1 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).. … WebDec 31, 2024 · Two of the altered genes were of particular interest with respect to PMN formation: thrombospondin‐1 (TSP1; THBS1) was the most significantly downregulated gene, while the chondroitin sulfate proteoglycan, … うるま市 求人 主婦 パート
006141 - TSP1- Strain Details - The Jackson Laboratory
WebJan 14, 2024 · We tested whether TSP1 plays an important role in fibroblast activation and found the mRNA expression of Thbs1 significantly increased by IH as compared with normoxia in mPCFs . In addition, IH significantly increased the protein level of TSP1 beginning from 2 hr and sustained until 8 hr in mPCFs (Figure 3F–G). WebSecreted TSP1 is a glycoprotein with a molecular mass of 150-180 kDa. Protocols. Product Specific Protocols; WB protocol for Thrombospondin 1 antibody 18304-1-AP: Download … WebSep 1, 2008 · Thrombospondin-1 (TSP1/THBS1) plays a major role in the pathophysiology of rheumatoid arthritis (RA); however, its interface with the cytokine network involved in RA has not been delineated. うるま市水道局 口座振替