Grb2 molecular weight
WebJun 24, 2015 · The adaptor protein growth factor receptor-bound protein 2 (Grb2) is ubiquitously expressed in eukaryotic cells and involved in a multitude of intracellular protein interactions. Grb2 plays a pivotal role in tyrosine kinase-mediated signal transduction including linking receptor tyrosine kinases to … WebResults: As example, high mRNA expression in tumor tissue compared to analogous normal tissue of c-MET and its ligand HGF correlated in silico with shorter overall survival (OS; p < 0.0001) and may constitute an independent prognostic marker for outcome of patients with metastatic solid tumors, suggesting a strategy to identify patients most likely to benefit …
Grb2 molecular weight
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WebThe single MAP2 gene produces four major transcripts producing four proteins, MAP2A, MAP2B, MAP2C and MAP2D. MAP2A and MAP2B are very high molecular weight proteins, with apparent molecular weight on SDS-PAGE about 250kDa, while MAP2C and MAP2D are much lower molecular weight forms with apparent SDS-PAGE size about … WebMolecular Weight of GRB2: 25-31 kDa. Positive Controls: COLO 320DM cell lysate: sc-2226, NIH/3T3 whole cell lysate: sc- 2210 or A-431 whole cell lysate: sc-2201. STORAGE Store at 4° C, **DO NOT FREEZE**. Stable for one year from the date of shipment. Non-hazardous. No MSDS required.
WebThe molecular weight of Grb2 is 25,206.35 Da, and the theoretical isoelectric point of the protein, as calculated using the molecular database ExPASy, is 5.89 (10). The protein is … WebSOURCE Weight Standards detected with GRB2 (C-7) is a mouse monoclonal antibody raised against amino acids 54-164 mapping to a central domain of GRB2 of mouse origin. ... Molecular Weight of GRB2: 25-31 kDa. Positive Controls: KNRK whole cell lysate: sc-2214, HL-60 whole cell lysate: sc-2209 or MOLT-4 cell lysate: sc-2233.
WebReactivity: Rat (QC Testing), Human, Mouse, Dog, Chicken, Frog (Tested in Development) Isotype: Mouse IgG1. Immunogen: Rat GRB2 aa. 1-217. Application: Western blot … WebJul 18, 2024 · By using the Rad51 antibody after chemical cross-linking, a band of relatively high molecular weight (ca. 119 kDa; approximate to the sum of molecular weights for Rad51, PTEN, and Grb2) was ...
WebThe strongest of these bands had an apparent molecular mass of 36-38 kDa on SDS gels, and it was quantitatively removed from the lysates by adsorption to a fusion protein …
WebCalculated molecular weight: 25 kDa: Observed molecular weight: 25-28 kDa: GenBank accession number: BC000631: Gene symbol: GRB2: Gene ID (NCBI) 2885: Conjugate: … how many carbs per meal for a diabeticGrb2 is best known for its ability to link the epidermal growth factor receptor tyrosine kinase to the activation of Ras and its downstream kinases, ERK1,2. Grb2 is composed of an SH2 domain flanked on each side by an SH3 domain. Grb2 has two closely related proteins with similar domain organizations, Gads … See more Growth factor receptor-bound protein 2 also known as Grb2 is an adaptor protein involved in signal transduction/cell communication. In humans, the GRB2 protein is encoded by the GRB2 gene. The protein … See more Grb2 is widely expressed and is essential for multiple cellular functions. Inhibition of Grb2 function impairs developmental processes in various organisms and blocks … See more Grb2 has been shown to interact with: • ADAM15, • Abl gene, • Arachidonate 5-lipoxygenase, • B-cell linker, • BCAR1, See more • GRB2+Adaptor+Protein at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • The Grb2 protein page on The SH2 Website See more The SH2 domain of Grb2 binds to phosphorylated tyrosine-containing peptides on receptors or scaffold proteins with a preference for pY-X-N-X, where X is generally a hydrophobic residue such as valine (see [1]). The See more • MAPK/ERK pathway See more • Colledge M, Froehner SC (May 1998). "Interaction between the nicotinic acetylcholine receptor and Grb2. Implications for … See more high school band bannersWebMay 1, 2002 · All GFP chimeric molecules in this study demonstrated the expected apparent molecular weight by western blotting using an anti-GFP antibody (52 kDa for Grb2-YFP … how many carbs per hard boiled eggWebJul 13, 2024 · Grb2 has been discovered to form complexes with a range of cellular proteins and o have roles in cell growth, cell proliferation, metabolism, embryogenesis, and cancer cell differentiation [ 4, 5... high school band director salary texashigh school band directors directoryWebIndeed, Grb2 is a key component of a signaling pathway that controls a very early cell fate decision in the developing mouse embryo, by promoting the induction of genes required for the differentiation of primitive endoderm, while inhibiting the expression of genes required for the epiblast lineage [83]. high school band drum chartsWebApr 29, 2014 · As shown in Figure 1 D, the SUMO1-GST-Grb2 with higher molecular weight of approximately 70 kDa was detected in the E.coli transformed with pE1E2S1 … high school band concerts